What is Vitamin B6?

Vitamin B6 is a water-soluble vitamin found in foods like chickpeas, salmon, poultry, potatoes and bananas. The body converts it into its active form, pyridoxal 5'-phosphate (P5P), which helps more than 100 enzymes do their jobs, most of them involved in breaking down and building amino acids.*

Why it's in Advanced Kidney Support

One of B6's jobs is steering a compound called glyoxylate away from becoming oxalate. Less oxalate means less material available to bind with calcium in the urine, which is the most common way kidney stones form.* B6 needs also tend to run higher in people with kidney concerns, and low B6 status is common in that group.*

What the research shows

• Human study (Journal of the American Society of Nephrology, 1999): Researchers followed 85,557 women for 14 years. Women with the highest vitamin B6 intake had a 34% lower risk of developing kidney stones than those with the lowest intake.*

This was an observational study, which shows an association rather than cause and effect.

How much is in each serving

Each 2-capsule serving provides 30 mg, or 1,765% of the Daily Value. That sounds high, but the Daily Value (1.7 mg) is set to prevent deficiency, not to support oxalate metabolism. 30 mg is well below the U.S. upper limit of 100 mg per day for adults.

Good to know

• Very high B6 intake over long periods (typically well above 100 mg a day) has been linked to nerve symptoms like tingling. If you take other B-complex or multivitamin products, add up your total B6.
• Talk with your provider if you take levodopa, phenytoin or other medications known to interact with B6.

Frequently asked questions

What form of Vitamin B6 is in Advanced Kidney Support?

Pyridoxine hydrochloride (pyridoxine HCl), a stable, well-studied form that the body converts to active P5P.

Can I get enough B6 from food?

Most people get enough to prevent deficiency from food. The 30 mg in Advanced Kidney Support is a supplemental amount chosen to support healthy oxalate processing.*

Sources

1. Curhan GC, Willett WC, Speizer FE, Stampfer MJ. Intake of vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol. 1999;10(4):840-845. PMID: 10203369
2. National Institutes of Health, Office of Dietary Supplements. Vitamin B6 Fact Sheet for Health Professionals.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.