Targeted Prostate Flow Two-Bottle Bundle
Maximizes peak stream velocity & complete bladder emptying.*
Rapidly relieves deep pelvic swelling, edema, & heavy tightness.*
Calms sudden flare-ups & triggers for nighttime bathroom trips.*
Provides advanced cellular protection to guard tissue density.*
101 Day Money Back Guarantee
Double the Supply. Uncompromised Daily Prostate Support.*
Save 10% and keep your daily health routine completely seamless. Our Targeted Prostate Flow Duo packages a full 60-day supply of our flagship formula into two bottles. Physician-formulated to support the body's natural male networks, this powerful routine optimizes smooth urinary tract flow, balances hormone modulation pathways, and promotes long-term cellular resilience.*
By securing a 2-bottle bundle, you ensure consistent, uninterrupted defense for your body's vital systems while enjoying a compounding 10% savings on every delivery.
SUGGESTED USE
Take 3 capsules, two times daily or as recommended by your health-care practitioner.
INGREDIENTS
- Coptis Root Extract 10:1
- Organic Pumpkin Seed Extract 10:1
- Cleavers Herb Extract 10:1
- Organic Skullcap Root Extract 4:1
- Organic Nettle Leaf Extract 10:1
- Organic Ginger Root Extract 10:1
- Organic Green Tea Leaf Extract 10:1
- Chinese Rhubarb Root Extract 10:1
- Fritillaria thumbergii Bulb Powder
- Beta Sitosterol (From Phytosterol)
- Organic Cassia Bark Powder (Cinnamon)
THE NO LIST
- No gluten
- No GMOs
- No hormones or antibiotics
- No dairy or eggs
- No soy
- No fat, sugar or oils
- No casein
- No artificial additives
- No binders, fillers or anti-caking agents
CERTIFICATION & TESTING
- Certified Non-GMO
- Certified Gluten Free
- Tested for Heavy Metals & Microbiological Contaminants
- Made in the USA in FDA-certified facilities
- Third-party testing on every batch
Choose options
WHAT TO EXPECT WHEN USED AS DIRECTED
MONTH 1 Expect a gentle easing of pelvic tension, less daily urgency, and a welcome drop in post-urination fullness or discomfort.*
MONTH 2 Sleep improves as disruptive nighttime awakenings slow down. The urinary stream becomes steadier, with a noticeable increase in volume.*
MONTH 3 Straining stops as a significantly stronger flow returns. This phase also brings a steady lift in intimate wellness, including enhanced libido and a return to satisfying intimacy.*
MONTH 6+ Expect a consistently strong urinary flow, and a normal, pain-free return to intimacy.*
Every body is unique. Results may vary, and long-term consistency is the most important step toward wellness.
A multi-pathway clinical protocol engineered to address the four root drivers of prostate stress — far beyond what single-ingredient alternatives can achieve.*
Stops Sudden Pelvic Flare-Ups*
Relieves Heavy, Blocked Pelvic Tightness*
Shields Gland Tissue from Abnormal Growth*
Reduces Swelling & Nighttime Bathroom Trips*
Blocks Gland Overgrowth & Unlocks Stream Velocity*
AXO
Others
THE SCIENCE BEHIND THE INGREDIENTS
Coptis Root Extract
Microbial Clearing & Deep Pelvic Soothing*
A highly potent bitter herb traditionally used for deep systemic clearing. Dr. Chris selected this 10:1 extract to actively target microbial stressors and calm deep-seated pelvic inflammation, providing a clean foundation for long-term urinary tract comfort.*
Organic Pumpkin Seed Extract
Prostate Size & Muscle Tone*
Packed with essential fatty acids, phytosterols, protective zinc, and natural magnesium. This concentrated extract works directly on the physical size and tone of the prostate gland, helping to relax the surrounding smooth muscle tissue to support a steady, unobstructed urinary flow.*
Cleavers Herb Extract
Pelvic Lymph & Drainage Support*
A classic botanical valued for its fluid-moving properties. It works systematically to clear lymphatic congestion in the pelvic region and flush out stagnation, ensuring a smooth, natural drainage process throughout the entire urinary tract.*
Organic Skullcap Root Extract
Natural 5-Alpha Reductase Inhibitor*
A powerful botanical chosen for its direct action against prostate enlargement (BPH). It functions as a natural 5-alpha reductase inhibitor to help regulate hormone pathways, soothe deep chronic inflammation, and protect prostate cells from abnormal proliferation.*
Organic Nettle Leaf Extract
Proven Prostate Volume & PSA Support*
A clinically backed botanical that directly counteracts the root drivers of prostate enlargement. Multiple clinical trials demonstrate that Nettle Leaf delivers significant reductions in prostate volume and lowers PSA scores compared to a placebo. It achieves this by functioning as a natural 5-alpha reductase inhibitor and directly interfering with SHBG binding—blocking the hormonal signals that trigger abnormal tissue growth and disrupt daily flow.*
Organic Ginger Root Extract
Metabolic Balance & Formula Synergy*
A crucial balancing agent with deep anti-inflammatory benefits. Because ginger is naturally warming, Dr. Chris explicitly included it to perfectly counter the intense "coldness" of Coptis, creating a harmonized formula that is gentle on the digestive tract. Its highly active gingerols work systematically to help manage blood sugar and lipid levels—directly addressing the complex metabolic factors that can quietly contribute to BPH and prostate tissue changes.*
Organic Green Tea Leaf Extract
Advanced Cellular Growth Regulation*
Standardized for maximum polyphenol power and loaded with catechins (including EGCG-rich extracts). The active compounds in this clean extract provide deep, targeted protection for prostate tissue at a cellular level. It functions as a powerful regulator, actively defending the gland against abnormal cellular proliferation and the long-term structural tissue changes that can disrupt prostate wellness.*
Chinese Rhubarb Root Extract
Pelvic Stagnation & Damp Heat Clearing*
A deeply clearing botanical selected for its traditional role in resolving pelvic stagnation. In herbal traditions, it is used to specifically clear "Damp Heat"—the heavy, metabolic accumulation in the lower abdomen that compromises prostate comfort. It provides robust antimicrobial support to target unwanted microbial stressors, cool localized heat, and maintain a clear, healthy pelvic environment.*
Fritillaria Thunbergii Bulb Powder
Tissue Soothing & Cleansing Support*
A highly specialized traditional herb used to cool localized heat and ease the intense physical discomfort of an angry, swollen prostate. While it works from the inside out to soothe deep pelvic irritation, its unique cleansing properties actively help clear away the metabolic congestion that can cause the gland to feel heavy, tight, and blocked—restoring a sense of comfort and ease.*
Beta-Sitosterol
Bladder Emptying & Stream Velocity*
The heaviest-hitting compound for immediate urinary performance. Backed by rigorous clinical studies, this pure phytosterol is scientifically proven to significantly improve IPSS and AUA symptom scores, maximize complete bladder emptying, and boost peak stream velocity. Rather than shrinking the gland itself, it targets the root of urinary blockages by rapidly reducing local prostate inflammation and edema (tissue swelling), while helping to manage the broader metabolic factors that disrupt nighttime sleep.*
Organic Cassia Bark Powder
Circulatory Drive & Digestive Protection*
A foundational warming bark essential for full-formula harmony. Dr. Chris selected this highly active, sweet Yang botanical to deliver deep circulatory support to the lower abdomen and protect the digestive tract. By neutralizing the intense coldness of the heavy clearing herbs in this formula, it stabilizes the gut, supports healthy blood sugar balance, and provides mild antimicrobial action to ensure complete pelvic comfort without digestive disruption.*
Coptis Root Extract
Microbial Clearing & Deep Pelvic Soothing*
A highly potent bitter herb traditionally used for deep systemic clearing. Dr. Chris selected this 10:1 extract to actively target microbial stressors and calm deep-seated pelvic inflammation, providing a clean foundation for long-term urinary tract comfort.*
Organic Pumpkin Seed Extract
Prostate Size & Muscle Tone*
Packed with essential fatty acids, phytosterols, protective zinc, and natural magnesium. This concentrated extract works directly on the physical size and tone of the prostate gland, helping to relax the surrounding smooth muscle tissue to support a steady, unobstructed urinary flow.*
Cleavers Herb Extract
Pelvic Lymph & Drainage Support*
A classic botanical valued for its fluid-moving properties. It works systematically to clear lymphatic congestion in the pelvic region and flush out stagnation, ensuring a smooth, natural drainage process throughout the entire urinary tract.*
Organic Skullcap Root Extract
Natural 5-Alpha Reductase Inhibitor*
A powerful botanical chosen for its direct action against prostate enlargement (BPH). It functions as a natural 5-alpha reductase inhibitor to help regulate hormone pathways, soothe deep chronic inflammation, and protect prostate cells from abnormal proliferation.*
Organic Nettle Leaf Extract
Proven Prostate Volume & PSA Support*
A clinically backed botanical that directly counteracts the root drivers of prostate enlargement. Multiple clinical trials demonstrate that Nettle Leaf delivers significant reductions in prostate volume and lowers PSA scores compared to a placebo. It achieves this by functioning as a natural 5-alpha reductase inhibitor and directly interfering with SHBG binding—blocking the hormonal signals that trigger abnormal tissue growth and disrupt daily flow.*
Organic Ginger Root Extract
Metabolic Balance & Formula Synergy*
A crucial balancing agent with deep anti-inflammatory benefits. Because ginger is naturally warming, Dr. Chris explicitly included it to perfectly counter the intense "coldness" of Coptis, creating a harmonized formula that is gentle on the digestive tract. Its highly active gingerols work systematically to help manage blood sugar and lipid levels—directly addressing the complex metabolic factors that can quietly contribute to BPH and prostate tissue changes.*
Organic Green Tea Leaf Extract
Advanced Cellular Growth Regulation*
Standardized for maximum polyphenol power and loaded with catechins (including EGCG-rich extracts). The active compounds in this clean extract provide deep, targeted protection for prostate tissue at a cellular level. It functions as a powerful regulator, actively defending the gland against abnormal cellular proliferation and the long-term structural tissue changes that can disrupt prostate wellness.*
Chinese Rhubarb Root Extract
Pelvic Stagnation & Damp Heat Clearing*
A deeply clearing botanical selected for its traditional role in resolving pelvic stagnation. In herbal traditions, it is used to specifically clear "Damp Heat"—the heavy, metabolic accumulation in the lower abdomen that compromises prostate comfort. It provides robust antimicrobial support to target unwanted microbial stressors, cool localized heat, and maintain a clear, healthy pelvic environment.*
Fritillaria Thunbergii Bulb Powder
Tissue Soothing & Cleansing Support*
A highly specialized traditional herb used to cool localized heat and ease the intense physical discomfort of an angry, swollen prostate. While it works from the inside out to soothe deep pelvic irritation, its unique cleansing properties actively help clear away the metabolic congestion that can cause the gland to feel heavy, tight, and blocked—restoring a sense of comfort and ease.*
Beta-Sitosterol
Bladder Emptying & Stream Velocity*
The heaviest-hitting compound for immediate urinary performance. Backed by rigorous clinical studies, this pure phytosterol is scientifically proven to significantly improve IPSS and AUA symptom scores, maximize complete bladder emptying, and boost peak stream velocity. Rather than shrinking the gland itself, it targets the root of urinary blockages by rapidly reducing local prostate inflammation and edema (tissue swelling), while helping to manage the broader metabolic factors that disrupt nighttime sleep.*
Organic Cassia Bark Powder
Circulatory Drive & Digestive Protection*
A foundational warming bark essential for full-formula harmony. Dr. Chris selected this highly active, sweet Yang botanical to deliver deep circulatory support to the lower abdomen and protect the digestive tract. By neutralizing the intense coldness of the heavy clearing herbs in this formula, it stabilizes the gut, supports healthy blood sugar balance, and provides mild antimicrobial action to ensure complete pelvic comfort without digestive disruption.*
HOW IT WORKS
AXOBOTANICA'S FOUR PILLAR FORMULA
Microbial Balance & Pelvic Comfort*
Supporting a clean internal environment and healthy inflammatory pathways to reduce localized congestion.*
Cellular Integrity & Antioxidant Defense*
Providing dense radical-scavenging protection to safeguard prostate tissue and support normal cellular life cycles.*
Microbial Balance & Pelvic Comfort*
Supporting a clean internal environment and healthy inflammatory pathways to reduce localized congestion.*
Cellular Integrity & Antioxidant Defense*
Providing dense radical-scavenging protection to safeguard prostate tissue and support normal cellular life cycles.*
Hormone Modulation & Size Support*
Balancing DHT pathways to support normal, healthy prostate architecture over time.*
Stronger Flow & Bladder Comfort*
Supporting a steady, reliable stream and fewer nighttime bathroom trips.*
Hormone Modulation & Size Support*
Balancing DHT pathways to support normal, healthy prostate architecture over time.*
Stronger Flow & Bladder Comfort*
Supporting a steady, reliable stream and fewer nighttime bathroom trips.*
A Message From Our Formulator
Why Standard Formulas Fall Short
The prostate is a vital gland responsible not only for reproductive function but for the structural and mechanical health of the lower urinary tract. In my clinical practice, I regularly consult with men seeking to maintain normal, healthy prostate architecture, balanced hormone pathways, and consistent fluid mechanics—critical factors that directly dictate sleep quality, daily comfort, and long-term vitality.
This is why I formulated Targeted Prostate Flow. Instead of relying on generic, single-ingredient saw palmetto shortcuts, we engineered a comprehensive, physician-formulated botanical matrix. By combining Cochrane-grade Beta-Sitosterol with standardized Nettle Root and Pumpkin Seed, this formula is clinically focused to support healthy urinary flow, reduce occasional urgency, and promote complete bladder emptying.
We paired this foundation with specialized traditional botanicals like Coptis (Berberine) and Chinese Skullcap to target deep, root-cause cellular pathways and localized pelvic comfort. We deliberately chose a completely clean manufacturing path, guaranteeing zero synthetic lubricants, flow agents, or hidden proprietary secrets. In my opinion, Axobotanica has established a new benchmark for clean and structural transparency, offering men a highly targeted, evidence-based routine to take a proactive approach to their health.
DR. CHRIS CHLEBOWSKI
Co-Founder & Chief Medical Officer of AXOBOTANICA | Naturopath, Homeopath & Clinical Herbalist
Research & Efficacy Data
In studies on its active components, Nettle Root, Beta-Sitosterol, Pumpkin Seed, and Chinese Skullcap were clinically shown to support healthy prostate volume, size, and urinary flow by directly balancing DHT pathways, acting as natural 5-alpha reductase inhibitors, and significantly improving IPSS scores in landmark human RCTs. This foundational action is paired with deep systemic protection: Green Tea Extract, Coptis Root, Ginger, and Cassia Bark have been demonstrated to reduce localized tissue inflammation, suppress macrophage-driven NF-kB pathways, alleviate chronic pelvic discomfort, and regulate advanced cellular growth. Finally, Cleavers, Chinese Rhubarb, and Fritillaria Bulb complement this matrix by optimizing pelvic lymph drainage, clearing structural stagnation, and relaxing prostatic smooth muscle contractions to promote uninterrupted fluid flow and total urinary comfort.*
(See 'Clinical Research' below in FAQ for sources)
You won’t see a USDA Organic seal on this bottle. WHY?
INTEGRITY OVER LABELS
To meet that regulatory 70% threshold, we would have had to sacrifice the clinical potency of the specific, wild-crafted botanicals Dr. Chris demanded for this formula.
Here’s what we did instead: We chose organic for every single ingredient where a premium option existed. We easily could have used standard, cheaper versions of our Pumpkin Seed, Nettle, and Ginger to save on production costs. Instead, we chose to pay more for organic sourcing on 54% of the formula because 'clean' isn't just a marketing buzzword for us—it’s our baseline.
Made in an FDA-certified USA facility to guarantee quality.
NO FILLERS OR BINDERS
VEGAN
NON-GMO
NO GLYPHOSATE
NO ARTIFICIAL ADDITIVES
NO FILLERS OR BINDERS
NO GLUTEN
NO HORMONES
NO ANTIBIOTICS
FAQs
This formula works by targeting multiple pathways simultaneously: it helps modulate the inflammatory response within glandular tissue, supports healthy cellular turnover, and aids in maintaining proper hormonal signaling. By promoting efficient lymphatic drainage and improving local circulation, it helps maintain the structural integrity and comfort of the prostate gland while supporting healthy, unobstructed urinary flow.
- Journal of Herbal Pharmacotherapy (2007): Comprehensive review of nettle root anti-inflammatory mechanisms (NF-kB, COX-1/2, and TNF-alpha inhibition). PMID: 17509841
- The Lancet (1995): Landmark randomized, double-blind, placebo-controlled trial demonstrating significant clinical improvements in urinary symptom scores and flow measures. PMID: 7540705
- Urologia Internationalis (2015): GRANU Study—Large randomized controlled trial (n=1,431) demonstrating a 58.5% responder rate and clinically relevant IPSS reduction over 12 months. PMID: 25196580
- Journal of Ethnopharmacology (2019): Scutellaria baicalensis suppresses androgen events in prostate tissue and inhibits BPH via 5a-reductase and apoptosis pathways. PMID: 30708034
- Cancer Research (2006): Human randomized controlled trial demonstrating a 3% vs. 30% progression rate in open-label groups alongside improved IPSS urinary symptom scores. PMID: 16424063
- Asian Journal of Andrology (2024): Berberine HCl alleviates CP/CPPS and reduces prostatic inflammation and oxidative stress via gut microbiome modulation. PMID: 39012524
- Cancer Prevention Research (2014): Active 6-shogaol isolates inhibit advanced prostate cancer cell survival and suppress inflammatory STAT3 and NF-kB signaling. PMID: 24691500
- ClinicalTrials.gov (NCT03946163): Pilot randomized controlled trial evaluating the therapeutic safety and efficacy of cinnamon compounds directly in chronic prostatitis patients. Identifier: NCT03946163
- Molecules (2020): Galium aparine extracts demonstrate significant immunostimulatory, antioxidant, and anti-inflammatory activity. PMID: 32824103
- Cancer Research (2005): Rhubarb-derived emodin directly targets and down-regulates the Androgen Receptor, inhibiting abnormal prostate cell growth. PMID: 15781642
- Food and Chemical Toxicology (2021): Comprehensive pharmacological review demonstrating that peimine isolates inhibit prostatic smooth muscle contraction and soothe localized pelvic pain pathways. PMID: 34029669
We utilize 10:1 extracts to ensure you receive a concentrated dose of the active compounds found in each herb. This "clean" extraction process allows us to provide higher potency in a smaller, more efficient serving size.
Beta-Sitosterol is a plant-derived sterol that is widely studied for its ability to support urinary function. It works by helping to modulate inflammatory pathways and supporting the overall comfort of the prostate gland.
Yes, this formula is designed to be taken as a consistent part of a daily wellness routine. By providing ongoing support for circulation, lymphatic health, and inflammation management, it helps maintain prostate health over time.